研究業績
Ａ．原著
| No. | 著者 ／ 題名 － 発表雑誌 巻：頁（始頁‐終頁），年 |
|---|---|
| 1 | Ishiguro H H, Arinami T, Yamada K, Otsuka Y, Toru M, Shibuya H. An association study between a transcriptional polymorphism in the serotonin transporter gene and panic disorder in a Japanese population. Psychiatry and Clinical Neuroscience. 51:333-335.1997. |
| 2 | Hayakawa T, Ishiguro H H, Toru M, Hamaguchi H, Arinami T. Systematic search for mutations in the 14-3-3 h Chain gene on chromosome 22 in schizophrenics. Psychiatric Genetics. 8:33-36.1998. |
| 3 | Ishiguro H H, Arinami T, Saito T, Akazawa S, Enomoto M, Mitushio H, Fujishiro H, Tada K, Akimoto Y, Mifune H, Shiozuka S, Hamaguchi H, Toru M, Shibuya H. Association study between the -141C Ins/Del and TaqI A polymorphisms of the dopamine D2 Receptor gene and alcoholism. Alcoholism: Clinical and Experimental Research. 22:845-848.1998. |
| 4 | Ishiguro H H, Ohtsuki T, Toru M, Itokawa M, Aoki J, Shibuya H, Kurumaji A, Yoshiro O, Iwawaki A, Ota K, Shimizu H, Hamaguchi H, Arinami T: Association between polymorphisms in the type 1 sigma receptor gene and schizophrenia. Neuroscience Letters. 257:45-48.1998. doi:10.1016/s0304-3940(98)00797-6. |
| 5 | Ishiguro H H, Arinami T, Saito T, Akazawa S, Enomoto M, fujishiro H, Tada K, Akimoto Y, Mifune H, Shiozuka S, Hamaguchi H, Toru M, Shibuya H: Systematic Search for Variations in the Tyrosine hydroxylase gene and their associations with schizophrenia, affective disorders and alcoholism. American Journal of Medical Genetics (Neuropsychiatric Genetics). 81:388-396.1998. |
| 6 | Ishiguro H H, Saito T, Shibuya H, Toru M, Arinami T: No association between C-45T polymorphism in the Sp1 binding site of the promoter region of the cholecystokinin gene and alcoholism. Psychiatry Research. 85:209-213.1999. doi:10.1016/s0165-1781(98)00127-9. |
| 7 | Arinami T, Ohtsuki T, Yamakawa-Kobayashi K, Amemiya H, Fujiwara H, Kawata K, Ishiguro H H, Hamaguchi H: A synergistic effect of serotonin transporter gene polymorphism and smoking in association with coronary heart disease. Thrombosis and Haemostasis. 81:853-856, 1999. |
| 8 | Okuyama Y, Ishiguro H H, Toru M, Arinami T: A genetic polymorphism in the promoter region of DRD4 associated with expression and schizophrenia. Biochemical & Biophysical Research Communications. 258:292-295.1999. doi:10.1006/bbrc.1999.0630. |
| 9 | Ishiguro H H, Saito T, Akazawa S, Mitsushio H, Tada K, Enomoto M, Mifune H, Hamaguchi H, Toru M, Shibuya H, Arinami T: An association study between drinking-related antisocial behavior and a polymorphism in the serotonin transporter gene in a Japanese population. Alcoholism: Clinical and Experimental Research. 23:1281-1284.1999. |
| 10 | Ishikawa H, Ohtsuki T, Ishiguro H H, Yamakawa-Kobayashi K, Endo K, Lin YL, Yanagi H, Tsuchiya S, Kawata K, Hamaguchi H, Arinami T: Association between serotonin transporter gene polymorphism and smoking among Japanese males. Cancer Epidemiology Biomarkers & Prevention. 8:831-833.1999. |
| 11 | Ishiguro H H, Shibuya H, Saito T, Arinami T: Association study between high and low activity polymorphism of catechol-O-methyltransferase gene and alcoholism. Psychiatric Genetics. 9:135-138.1999. |
| 12 | Ishiguro H H, Saito T, Shibuya H, Hamaguchi H, Arinami T: Mutation search for the 5’ region of the tryptophan hydroxylase gene and association study with alcoholism. Journal of Neural Transmission. 106:1017-1025.1999. doi:10.1007/s007020050220. |
| 13 | Ueno S, Nakamura M, Mikami M, Kondoh K, Ishiguro H H, Arinami T, Komiyama T, Mitsushio H, Sano A, Tanabe H: Identification of a novel polymorphism of the human dopamine transporter (DAT1) gene and the significant association with alcoholism. Molecular Psychiatry. 4:552-557.1999. |
| 14 | Arinami T, Iijima Y, Yamakawa-kobayashi K, Ishiguro H H, Ohtsuki T, Yanagi H, Shimakura Y, Ishikura H, Hamaguchi H: Supportive evidence for contribution of the dopamine D2 receptor gene to heritability of stature: linkage and association studies. Annals of Human Genetics. 63(Pt2):147-151.1999. doi:10.1046/j.1469-1809.1999.6320147.x. |
| 15 | Okuyama Y, Ishiguro H H, Shibuya H, Watanabe A, Arinami T: Identification of a polymorphism in the promoter region of DRD4 associated with the human personality trait of novelty seeking. Molecular Psychiatry. 5:64-69.2000. |
| 16 | Ohtsuki T, Ishiguro H H, Yoshikawa T, Arinami T: WFS1 gene mutation search in depressive patients: Detection of 5 missense polymorphisms but no association with depression or bipolar affective disorder. Journal of Affective Disorder. 58:11-17.2000. |
| 17 | Ishiguro H H, Saito T, Shibuya H, Arinami T: Association study between genetic polymorphisms in the 14-3-3 e chain and dopamine D4 receptor genes and alcoholism. Alcoholism: Clinical and Experimental Research. 24:343-347.2000. |
| 18 | Ishiguro H H, Okuyama Y, Toru M, Arinami T: Mutation and association analyses of the dopamine D3 receptor gene in schizophrenia patients: Identification of the Ala38Thr polymorphism and suggested association between DRD3 haplotypes and schizophrenia. Molecular Psychiatry. 5:433-438.2000. |
| 19 | Ishiguro H H, Saito T, Shibuya H, Toru M, Arinami T: Mutation and association analyses of the Fyn kinase gene with alcoholism and schizophrenia. American Journal of Medical Genetics. 96:716-720.2000. |
| 20 | Ishiguro H H, Ohtsuki T, Okubo Y, Kurumaji A, Arinami T: Association analysis of the pituitary adenyl cyclase activating peptide gene (PACAP) on chromosome 18p11 with schizophrenia and bipolar disorders. Journal of Neural Transmission. 108:849-854.2001. doi:10.1007/s007020170034. |
| 21 | Yoshikawa T, Kikuchi M, Saito K, Watanabe A, Yamada K, Shibuya H, Nankai M, Kurumaji A, Hattori E, Ishiguro H H, Shimizu H, Okubo Y, Toru M, Detera-Wadleigh SD: Evidence for association of the myo-inositol monophosphatase 2 (IMPA2) gene with schizophrenia in Japanese samples. Molecular Psychiatry. 6:202-210.2001. doi:10.1038/sj.mp.4000835. |
| 22 | Ishiguro H H, Okubo Y, Ohtsuki T, Yamakawa-Kobayashi K, Arinami T: Mutation analysis of the retinoid X receptor beta, nuclear-related receptor 1, and peroxisome proliferator-activated receptor-alpha genes in schizophrenia and alcohol dependence: possible haplotype association of nuclear-related receptor 1 gene to alcohol dependence. American Journal of Medical Genetics. 114:15-23.2002. doi:10.1002/ajmg.1620. |
| 23 | Yamakawa-Kobayashi K, Ishiguro H H, Arinami T, Miyazaki R, Hamaguchi H: A Val227Ala polymorphism in the peroxisome proliferator activated receptor alpha (PPARA) gene is associated with variations in serum lipids levels. Journal of Medical Genetics. 39:189-191.2002. doi:10.1136/jmg.39.3.189. |
| 24 | Ohtsuki T, Ishiguro H H, Detera-Wadleigh SD, Toyota T, Shimizu H, Yamada K, Yoshitsugu K, Hattori E, Yoshikawa T, Arinami T: Association between serotonin 4 receptor gene polymorphisms and bipolar disorder in Japanese case-control samples and the NIMH Genetics Initiative Bipolar Pedigrees. Molecular Psychiatry. 7:954-961.2002. doi:10.1038/sj.mp.4001133. |
| 25 | The Japanese Schizophrenia Sib-pair Linkage Group (JSSLG) Arinami T, Ishiguro H H, Minowa Y, Ohtsuki T, Tsujita T, Imamura A, Yoshikawa T, Toyota T, Yamada K, Shimizu H, Yoshitsugu K, Shibata H, Fujii Y, Fukumaki Y, Tashiro N, Inada T, Iijima Y, Kitao Y, Furuno T, Someya T, Muratake T, Kaneko N, Tsuji S, Mineta M, Takeichi M, Ujike H, Takehisa Y, Tanaka Y, Nakata K, Kitajima T, Nishiyama T, Yamanouchi Y, Iwata N, Ozaki N, Ohara K, Shibuya H, Ohara K, Suzuki Y, Ohmori O, Shinkai T, Hori H, Nakamura J, Kojima T, Takahashi S, Tanabe E, Yara K, Nanko S, Yoneda H, Koh J, Sakai J, Inada Y, Kusumi I, Kameda K, Koyama T, Fukuzako H, Hashiguchi T, Tanabe K, Okazaki Y: Initial genome-wide scan for linkage with schizophrenia in the Japanese Schizophrenia Sib-pair Linkage Group (JSSLG) families. American Journal of Medical Genetics. 120B:22-28.2003. doi:10.1002/ajmg.b.20022. |
| 26 | Horiuchi Y, Nakayama J, Ishiguro H H, Ohtsuki T, Detera-Wadleigh SD, Toyota T, Yamada K, Nankai M, Shibuya H, Yoshikawa T, Arinami T: Possible association between a haplotype of the GABA-A receptor alpha 1 subunit gene (GABRA1) and mood disorders. Biological Psychiatry. 55:40-45.2004. doi: 10.1016/s0006-3223(03)00689-9. |
| 27 | Ohtsuki T, Tanaka S, Ishiguro H H, Tanabe E, Yara K, Okubo T, Takahashi S, Matsuura M, Sakai T, Muto M, Matsushima E, Noguchi E, Toru M, Inada T, Kojima T, Arinami T: Failure to find association between PRODH deletion and schizophrenia: population screening using simple PCR method. Schizophrenia Research. 67:111-113.2004. doi:10.1016/s0920-9964(03)00160-9. |
| 28 | Zhang PW*, Ishiguro H H*, Ohtsuki T, Hess J, Carillo F, Walther D, Onaivi ES, Arinami T, Uhl GR (*equal contribution to the first authorship.): Human cannabinoid receptor 1: 5' exons, candidate regulatory regions, polymorphisms, haplotypes and association with polysubstance abuse. Molecular Psychiatry. 9:916-931.2004. doi:10.1038/sj.mp.4001560. |
| 29 | Arinami T, Ohtsuki T, Ishiguro H H, Ujike H, Tanaka Y, Morita Y, Mineta M, Tkeichi M, Yamada S, Imamura A, Ohara K, Shibuta H, Ohara K, Suzuki Y, Muratake T, Kaneko N, Someya T, Inada T, Yoshikawa T, Toyota T, Yamada K, Kojima T, Takahashi S, Osamu O, Shinkai T, Nakamura M, Fukuzako H, Hashiguchi T, Niwa SI, Ueno T, Tachikawa H, Hori T, Asada T, Nanko S, Kunugi H, Hashimoto R, Ozaki N, Iwara N, Harano M, Arai H, Ohnuma T, Kusumi I, Koyama T, Yoneda H, Fukumaki Y, Shibata H, aneko S, Higuchi H, Yasui-Furukori N, Numachi Y, Itokawa M, Okazaki Y: Japanese Schizophrenia Sib-Pair Linkage Group. Genomewide high-density SNP linkage analysis of 236 Japanese families supports the existence of schizophrenia susceptibility loci on chromosomes 1p, 14q, and 20p. American Journal of Human Genetics. 77:937-944.2005. doi:10.1086/498122. |
| 30 | Gong JP, Onaivi ES, Ishiguro H H, Liu QR, Tagliaferro PA, Brusco A, Uhl GR: Cannabinoid CB2 receptors: immunohistochemical localization in rat brain. Brain Research. 1071:10-23.2006. doi:10.1016/j.brainres.2005.11.035. |
| 31 | Ishiguro H H, Liu QR, Gong JP, Hall FS, Ujike H, Morales M, Sakurai T, Grumet M, Uhl GR: NrCAM in addiction vulnerability: positional cloning, drug-regulation, haplotype-specific expression, and altered drug reward in knockout mice. Neuropsychopharmacology. 31:572-584. 2006. doi:10.1038/sj.npp.1300855. |
| 32 | Fukuda Y, Koga M, Arai M, Noguchi E, Ohtsuki T, Horiuchi Y, Ishiguro H H, Niizato K, Iritani S, Itokawa M, Arinami T: Monoallelic and Unequal Allelic Expression of the HTR2A Gene in Human Brain and Peripheral Lymphocytes. Biological Psychiatry. 60:1331-1335.2006. doi:10.1016/j.biopsych.2006.06.024. |
| 33 | Ishiguro H H, Horiuchi Y, Koga M, Inada T, Iwata N, Ozaki N, Ujike H, Muratake T, Someya T, Arinami T: RGS4 is not a susceptibility gene for schizophrenia in Japanese: Association study in a large case-control population. Schizophrenia Research. 89:161-164.2007. doi:10.1016/j.schres.2006.09.015. |
| 34 | Horiuchi Y, Ishiguro H H, Koga M, Inada T, Iwata N, Ozaki N, Ujike H, Muratake T, Someya T, Arinami T: Support for association of the PPP3CC gene with schizophrenia. Molecular Psychiatry. 12:891-893.2007. doi:10.1038/sj.mp.4002019. |
| 35 | Ishiguro H H, Iwasaki S, Teasenfitz L, Higuchi S, Horiuchi Y, Saito T, Arinami T, Onaivi ES: Involvement of cannabinoid CB2 receptor in alcohol preference in mice and alcoholism in humans. Pharmacogenomics Journal. 7:380-385.2007. doi:10.1038/sj.tpj.6500431. |
| 36 | Ishiguro H H, Walther D, Arinami T, Uhl GR: Variation in a bicarbonate cotransporter gene family member SLC4A7 is associated with propensity to addictions: a study using fine-mapping and three samples. Addiction. 102:1320-1325.2007. doi:10.1111/j.1360-0443.2007.01877.x. |
| 37 | Iwasaki S, Ishiguro H H, Higuchi S, Onaivi ES, Arinami T: Association study between alcoholism and endocannabinoid metabolic enzyme genes encoding fatty acid amide hydrolase and monoglyceride lipase in Japanese population. Psychiatric Genetics. 17:215-220.2007. doi:10.1097/YPG.0b013e32809913d8. |
| 38 | Koga M, Ishiguro H H, Horiuchi Y, Albalushi T, Inada T, Iwata N, Ozaki N, Ujike H, Muratake T, Someya T, Arinami T: Failure to confirm the association between the FEZ1 gene and schizophrenia in a Japanese population. Neuroscience Letters. 417:326-329.2007. doi:10.1016/j.neulet.2007.02.055. |
| 39 | Ishiguro H H, Koga M, Horiuchi Y, Inada T, Iwata N, Ozaki N, Ujike H, Muratake T, Someya T, Arinami T: PICK1 is not a susceptibility gene for schizophrenia in a Japanese population: Association study in a large case-control population. Neuroscience Research. 58:145-148.2007. doi:10.1016/j.neures.2007.02.008. |
| 40 | Ohtsuki T, Koga M, Ishiguro H H, Horiuchi Y, Arai M, Niizato K, Itokawa M, Inada T, Iwata N, Iritani S, Ozaki N, Kunugi H, Ujike H, Watanabe Y, Someya T, Arinami T: A polymorphism of the metabotropic glutamate receptor mGluR7 (GRM7) gene is associated with schizophrenia. Schizophrenia Research. 101:9-16.2008. doi:10.1016/j.schres.2008.01.027. |
| 41 | Onaivi ES, Ishiguro H H, Gong JP, Patel S, Meozzi PA, Myers L, Perchuk A, Mora Z, Tagliaferro PA, Gardner E, Brusco A, Akinshola BE, Hope B, Lujilde J, Inada T, Iwasaki S, Macharia D, Teasenfitz L, Arinami T, Uhl GR: Brain Neuronal CB2 Cannabinoid Receptors in Drug Abuse and Depression: From Mice to Human Subjects. PLoS ONE. 3:e1640.2008. doi:10.1371/journal.pone.0001640. |
| 42 | Inada T, Koga M, Ishiguro H H, Horiuchi Y, Syu A, Yoshio T, Takahashi N, Ozaki N, Arinami T: Pathway-based association analysis of genome-wide screening data suggests that genes associated with the GABA receptor signaling pathway are involved in neuroleptic-induced treatment-resistant tardive dyskinesia. Pharmacogenetics and Genomics. 18:317-323.2008. doi:10.1097/FPC.0b013e3282f70492. |
| 43 | Ishiguro H H, Gong JP, Hall FS, Arinami T, Uhl GR: Association of PTPRB gene polymorphism with drug addiction. American Journal of Medical Genetics Part B Neuropsychiatric Genetics. 147B:1167-1172.2008. doi:10.1002/ajmg.b.30742. |
| 44 | Ohtsuki T, Horiuchi Y, Koga M, Ishiguro H H, Inada T, Iwata N, Ozaki N, Ujike H, Watanabe Y, Someya T, Arinami T: Association of polymorphisms in the haplotype block spanning the alternatively spliced exons of the NTNG1 gene at 1p13.3 with schizophrenia in Japanese populations. Neuroscience Letters. 435:255-256.2008. doi:10.1016/j.neulet.2008.02.053. |
| 45 | Albalushi T, Horiuchi Y, Ishiguro H H, Koga M, Inada T, Iwata N, Ozaki N, Ujike H, Watanabe Y, Someya T, Arinami T: Replication study and meta-analysis of the genetic association of GRM3 gene polymorphisms with schizophrenia in a large Japanese case-control population. American Journal of Medical Genetics Part B Neuropsychiatric Genetics. 147:392-396.2008. doi:10.1002/ajmg.b.30610. |
| 46 | Ishiguro H H, Imai K, Koga M, Horiuchi Y, Inada T, Iwata N, Ozaki N, Ujike H, Itokawa M, Kunugi H, Sasaki T, Watanabe Y, Someya T, Arinami T: Replication study for associations between polymorphisms in the CLDN5 and DGCR2 genes in the 22q11 deletion syndrome region and schizophrenia. Psychiatric Genetics. 18:255-256.2008. doi:10.1097/YPG.0b013e328306c7dc. |
| 47 | Koga M, Ishiguro H H, Yazaki S, Horiuchi Y, Arai M, Niizato K, Iritani S, Itokawa M, Inada T, Iwata N, Ozaki N, Ujike H, Kunugi H, Sasaki T, Takahashi M, Watanabe Y, Someya T, Kakita A, Takahashi H, Nawa H, Muchardt C, Yaniv M, Arinami T: Involvement of SMARCA2/BRM in the SWI/SNF chromatin-remodeling complex in schizophrenia. Human Molecular Genetics. 18:2483-2494.2009. doi:10.1093/hmg/ddp166. |
| 48 | Onaivi ES, Ishiguro H H, Liu QR, Gong JP, Tagliaferro P, Brusco A, Arinami T, Uhl GR: CNS effects of CB2 cannabinoid receptors. The Open Neuropsychopharmacology Journal. 2:45-52.2009. doi:10.2174/1876523800902020045. |
| 49 | Liu QR, Pan CH, Hishimoto A, Xi ZX, Llorente-Berzal A, Viveros MP, Ishiguro H H, Arinami T, Onaivi ES, Uhl GR: Species differences in cannabinoid receptor 2 (CNR2 gene): identification of novel human and rodent CB2 isoforms, differential tissue expression, and regulation by cannabinoid receptor ligands. Genes Brain and Behavior. 8:519-531.2009. doi:10.1111/j.1601-183X.2009.00498.x. |
| 50 | Ishiguro H H, Carpio O, Horiuchi Y, Shu A, Higuchi S, Schanz N, Benno R, Arinami T, Onaivi ES: A nonsynonymous polymorphism in cannabinoid CB2 receptor gene is associated with eating disorders in humans and food intake is modified in mice by its ligands. Synapse. 64:92-96.2010. doi:10.1002/syn.20714. |
| 51 | Syu A, Ishiguro H H, Inada T, Horiuchi Y, Tanaka S, Ishikawa M, Arai M, Itokawa M, Niizato K, Iritani S, Ozaki N, Takahashi M, Kakita A, Takahashi H, Nawa H, Keino-Masu K, Arikawa-Hirasawa E, Arinami T: Association of the HSPG2 gene with neuroleptic-induced tardive Dyskinesia. Neuropsychopharmacology. 35:1155-1164.2010. doi: 10.1038/npp.2009.220. |
| 52 | Amagane H, Watanabe Y, Kaneko N, Nunokawa A, Muratake T, Ishiguro H H, Arinami T, Ujike H, Inada T, Iwata N, Kunugi H, Sasaki T, Hashimoto R, Itokawa M, Ozaki N, Someya T: Failure to find an association between myosin heavy chain 9, non-muscle (MYH9) and schizophrenia: a three-stage case-control association study. Schizophrenia Research. 118:106-112.2010. doi:10.1016/j.schres.2010.01.023. |
| 53 | Ishiguro H H, Horiuchi Y, Ishikawa M, Koga M, Imai K, Suzuki Y, Morikawa M, Inada T, Watanabe Y, Takahashi M, Someya T, Ujike H, Iwata N, Ozaki N, Onaivi ES, Kunugi H, Sasaki T, Itokawa M, Arai M, Niizato K, Iritani S, Naka I, Ohashi J, Kakita A, Takahashi H, Nawa H, Arinami T: Brain cannabinoid CB2 receptor in schizophrenia. Biological Psychiatry. 67:974-982.2010. doi:10.1016/j.biopsych.2009.09.024. |
| 54 | Koga M, Ishiguro H H, Horiuchi Y, Inada T, Ujike H, Itokawa M, Otowa T, Watanabe Y, Someya T, Arinami T: Replication study of association between ADCYAP1 gene polymorphisms and schizophrenia. Psychiatric Genetics. 20:123-125.2010. doi:10.1097/YPG.0b013e32833a1f52. |
| 55 | Yazaki S, Koga M, Ishiguro H H, Inada T, Ujike H, Itokawa M, Otowa T, Watanabe Y, Someya T, Iwata N, Kunugi H, Ozaki N, Arinami T: An association study between the dymeclin gene and schizophrenia in the Japanese population. Journal of Human Genetics. 55:631-634.2010. doi:10.1038/jhg.2010.72. |
| 56 | Ishiguro H H, Koga M, Horiuchi Y, Noguchi E, Morikawa M, Suzuki Y, Arai M, Niizato K, Iritani S, Itokawa M, Inada T, Iwata N, Ozaki N, Ujike H, Kunugi H, Sasaki T, Takahashi M, Watanabe Y, Someya T, Kakita A, Takahashi H, Nawa H, Arinami T: Supportive evidence for reduced expression of GNB1L in schizophrenia. Schizophrenia Bulletin. 36:756-765.2010. doi:10.1093/schbul/sbn160. |
| 57 | Onaivi ES, Benno R, Halpern T, Mehanovic M, Schanz N, Sanders C, Yan X, Ishiguro H H, Liu QR, Berzal AL, Viveros MP, Ali SF: Consequences of Cannabinoid and Monoaminergic System Disruption in a Mouse Model of Autism Spectrum Disorders. Current Neuropharmacology. 9:209-214.2011. doi:10.2174/157015911795017047. |
| 58 | Saetre P, Vares M, Werge T, Andreassen OA, Arinami T, Ishiguro H H, Nanko S, Tan EC, Han DH, Roffman JL, Muntjewerff JW, Jagodzinski PP, Kempisty B, Hauser J, Vilella E, Betcheva E, Nakamura Y, Regland B, Agartz I, Hall H, Terenius L, Jönsson EG: Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and age of onset in schizophrenia: A combined analysis of independent samples. American Journal of Medical Genetics Part B Neuropsychiatric Genetics. 156:215-224.2011. doi:10.1002/ajmg.b.31160. |
| 59 | Ishiguro H H, Onaivi ES, Horiuchi Y, Imai K, Komaki G, Ishikawa T, Suzuki M, Watanabe Y, Ando T, Higuchi S, Arinami T: Functional polymorphism in the GPR55 gene is associated with anorexia nervosa. Synapse. 65:103-108.2011. doi:10.1002/syn.20821. |
| 60 | Horiuchi Y, Iida S, Koga M, Ishiguro H H, Iijima Y, Inada T, Watanabe Y, Someya T, Ujike H, Iwata N, Ozaki N, Kunugi H, Tochigi M, Itokawa M, Arai M, Niizato K, Iritani S, Kakita A, Takahashi H, Nawa H, Arinami T: Association of SNPs linked to increased expression of SLC1A1 with schizophrenia. American Journal of Medical Genetics Part B Neuropsychiatric Genetics. 159B:30-37.2012. doi:10.1002/ajmg.b.31249. |
| 61 | Yoshida M, Shiroiwa K, Mouri K, Ishiguro H H, Supriyanto I, Ratta-Apha W, Eguchi N, Okazaki S, Sasada T, Fukutake M, Hashimoto T, Inada T, Arinami T, Shirakawa O, Hishimoto A: Haplotypes in the expression quantitative trait locus of interleukin-1β gene are associated with schizophrenia. Schizophrenia Research. 140:185-191.2012. doi:10.1016/j.schres.2012.06.031. |
| 62 | Tanaka S, Syu A, Ishiguro H H, Inada T, Horiuchi Y, Ishikawa M, Koga M, Noguchi E, Ozaki N, Someya T, Kakita A, Takahashi H, Nawa H, Arinami T: DPP6 as a candidate gene for neuroleptic-induced tardive dyskinesia. Pharmacogenomics Journal. 13:27-34.2013. doi:10.1038/tpj.2011.36. |
| 63 | Horiuchi Y, Ishikawa M, Kaito N, Iijima Y, Tanabe Y, Ishiguro H H, Arinami T: Experimental evidence for the involvement of PDLIM5 in mood disorders in hetero knockout mice. PLoS One. 8:e59320.2013. doi:10.1371/journal.pone.0059320. |
| 64 | Ishiguro H H, Hall FS, Horiuchi Y, Sakurai T, Hishimoto A, Grumet M, Uhl GR, Onaivi ES, Arinami T: NrCAM-regulating neural systems and addiction-related behaviors. Addiction Biology. 19:343-353.2014. doi:10.1111/j.1369-1600.2012.00469.x. |
| 65 | Ratta-Apha W, Mouri K, Boku S, Ishiguro H H, Okazaki S, Otsuka I, Sora I, Arinami T, Shirakawa O, Hishimoto A: A decrease in protein level and a missense polymorphism of KIF17 are associated with schizophrenia. Psychiatry Research. 230:424-429.2015. doi:10.1016/j.psychres.2015.09.031. |
| 66 | Liu QR, Canseco-Alba A, Zhang HY, Tagliaferro P, Chung M, Dennis E, Sanabria B, Schanz N, Escosteguy-Neto JC, Ishiguro H H, Lin Z, Sgro S, Leonard CM, Santos-Junior JG, Gardner EL, Egan JM, Lee JW, Xi ZX, Onaivi ES: Cannabinoid type 2 receptors in dopamine neurons inhibits psychomotor behaviors, alters anxiety, depression and alcohol preference. Scientific Reports. 7:17410.2017. doi:10.1038/s41598-017-17796-y. |
| 67 | Ishiguro H H, Higuchi S, Arinami T, Onaivi ES: Association between alcoholism and the gene encoding endocannabinoid synthesizing enzyme Diacylglycerol Lipase Alpha in Japanese population. Alcohol. 68:59-62.2018. doi:10.1016/j.alcohol.2017.09.005. |
| 68 | Ishiguro H H, Horiuchi Y, Tabata K, Liu QR, Arinami T, Onaivi ES: Cannabinoid CB2 Receptor Gene and Environmental Interaction in the Development of Psychiatric Disorders. Molecules. 23:e1836.2018. doi:10.3390/molecules23081836. |
| 69 | Canseco-Alba A, Schanz N, Ishiguro H H, Liu QR, Onaivi ES. Behavioral Evaluation of Seeking and Preference of Alcohol in Mice Subjected to Stress. Bio Protocol. 8:e3061.2018. doi:10.21769/BioProtoc.3061. |
| 70 | Ishiguro H H, Miyake K, Tabata K, Mochizuki C, Sakurai T, Onaivi ES. Neuronal cell adhesion molecule regulating neural systems underlying addiction. Neuropsychopharmacol Reports. 39:10-16.2019. doi:10.1002/npr2.12038. |
| 71 | Liu QR, Canseco-Alba A, Liang Y, Ishiguro H H, Onaivi ES. Low Basal CB2R in Dopamine Neurons and Microglia Influences Cannabinoid Tetrad Effects. International Journal of Molecular Sciences. 21:9763.2020. doi:10.3390/ijms21249763. |
| 72 | Kibret BG, Ishiguro H H, Horiuchi Y, Onaivi ES. New Insights and Potential Therapeutic Targeting of CB2 Cannabinoid Receptors in CNS Disorders. International Journal of Molecular Sciences. 23:975.2022. doi:10.3390/ijms23020975. |
| 73 | Ishiguro H H, Kibret BG, Horiuchi Y, Onaivi ES. Potential Role of Cannabinoid Type 2 Receptors in Neuropsychiatric and Neurodegenerative Disorders. Frontiers in Psychiatry. 13:828895.2022. doi:10.3389/fpsyt.2022.828895. |
| 74 | Nakajima K, Oka S, Tanikawa T, Nemoto-Sasaki Y, Matsumoto N, Ishiguro H H, Arata Y, Sugiura T, Yamashita A. Lysophosphatidylinositol Induced Morphological Changes and Stress Fiber Formation through the GPR55-RhoA-ROCK Pathway. International Journal of Molecular Sciences. 23:10932.2022. doi:10.3390/ijms231810932. |
| 75 | Tabassum T, Suzuki T, Iwata Y, Ishiguro H H. Depression and Associated Factors Among the Elderly Population in an Urban Tertiary Geriatric Hospital in Bangladesh. Gerontology and Geriatric Medicine. 9:23337214231178145.2023. doi:10.1177/23337214231178145. |
| 76 | Yamaguchi T, Yamada K, Nagai S, Nishikubo T, Koitabashi N, Minami-Hori M, Matsushima M, Shibata Y, Ishiguro H H, Sanai H, Fujikawa T, Takiguchi Y, Matsumoto KI, Kosho T. Clinical and molecular delineation of classical-like Ehlers-Danlos syndrome through a comprehensive next-generation sequencing-based screening system. Frontiers in Genetics. 14:1234804.2023. doi:10.3389/fgene.2023.1234804. |
| 77 | Canseco-Alba A, Tabata K, Momoki Y, Tabassum T, Horiuchi Y, Arinami T, Onaivi ES, Ishiguro H H. Cannabinoid CB2 receptors and hypersensitivity to methamphetamine: Vulnerability to schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 130:110924.2023. doi: 10.1016/j.pnpbp.2023.110924. |
| 78 | Ohashi Y, Shoji M, Hanawa K, Yokomichi H, Ishiguro H H. A parent-rating scale of postpartum depression: Maternity-monitoring scale by parents (MMSP). J Psychiatr Res. 171:197-206.2024. doi: 10.1016/j.jpsychires.2024.01.033. |
Ｂ．症例報告
| No. | 著者 ／ 題名 － 発表雑誌 巻：頁（始頁‐終頁），年 |
|---|---|
| 1 | Ishiguro H, Honobe N, Suzuki T, Tamai M, Nakane T. Transvestism recognized in Ehlers-Danlos syndrome: Report of two cases. Case Report in Psychiatry. 2019. Volume 2019 Article ID 7472301. doi:10.1155/2019/7472301. |
| 2 | Akita K, Kumakura Y, Nakajima E, Ishiguro H, Iijima T. Clonazepam for pain due to muscle spasm in a patient with vertebral compression fractures caused by multiple myeloma: a case report. JA Clinical Reports. 7:75.2021. doi: 10.1186/s40981-021-00477-1. |
Ｃ．総説
| No. | 著者 ／ 題名 － 発表雑誌 巻：頁（始頁‐終頁），年 |
|---|---|
| 1 | Arinami T, Ishiguro H, Onaivi ES. Polymorphisms in genes involved in neurotransmission in relation to smoking. European Journal of Pharmacology. 410:215-226.2000. doi:10.1016/s0014-2999(00)00816-5. |
| 2 | Onaivi ES, Ali SF, Chirwa SS, Zwiller J, Thiriet N, Akinshola BE, Ishiguro H. Ibogaine signals addiction genes and methamphetamine alteration of long-term potentiation. Annals of the New York Academy of Sciences. 965:28-46.2002. doi:10.1111/j.1749-6632.2002.tb04149.x. |
| 3 | Onaivi ES, Leonard CM, Ishiguro H, Zhang PW, Lin Z, Akinshola BE, Uhl GR. Endocannabinoids and cannabinoid receptor genetics. Progress in Neurobiology. 66:307-344.2002. |
| 4 | Onaivi ES, Ishiguro H, Gong JP, Patel S, Perchuk A, Meozzi PA, Myers L, Mora Z, Tagliaferro P, Gardner E, Brusco A, Akinshola BE, Liu QR, Hope B, Iwasaki S, Arinami T, Teasenfitz L, Uhl GR. Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain. Annals of the New York Academy of Sciences. 107:514-536.2006. doi:10.1196/annals.1369.052 |
| 5 | Onaivi ES, Carpio O, Ishiguro H, Schanz N, Uhl GR, Benno R. Behavioral Effects of CB2 Cannabinoid Receptor Activation and Its Influence on Food and Alcohol Consumption. Annals of the New York Academy of Sciences. 1139:426-433.2008. doi:10.1196/annals.1432.035. |
| 6 | Onaivi ES, Ishiguro H, Gu S, Liu QR. CNS effects of CB2 cannabinoid receptors: beyond neuro-immuno-cannabinoid activity. Journal of Psychopharmacology. 26:92-103.2012. doi:10.1177/0269881111400652. |
| 7 | Onaivi ES, Ishiguro H, Sgro S, Leonard CM. Cannabinoid Receptor Gene Variations in Drug Addiction and Neuropsychiatric Disorders. Journal of Drug and Alcohol Research. 2:Article ID 235714.2013. doi:10.4303/jdar/23571. |
| 8 | Ishiguro H, Onaivi ES. Beyond the Kraepelinian Dichotomy of Schizophrenia and Bipolar Disorder. Journal of Schizophrenia Research.4(1):1032.2017.Ishiguro H*, Yagasaki H, Horiuchi Y. Ehlers-Danlos Syndrome in the Field of Psychiatry: A Review. Frontiers in Psychiatry. 12:803898.2022. doi:10.3389/fpsyt.2021.803898. |
| 9 | Ishiguro H. Editorial: Targeting the endocannabinoidome in neurodegenerative disorders. Front Aging Neurosci. 14:1116635.2023. doi: 10.3389/fnagi.2022.1116635. |
| 10 | 石黒浩毅．アルコール依存症に関連する遺伝子多型、お茶の水医学誌. 45:63-87.1997. |
| 11 | 石黒浩毅、融通男．ベンゾジアゼピンと受容体、脳と神経の科学. 10:90-103.1998. |
| 12 | 石黒浩毅、有波忠雄．アルコール依存症に関連する遺伝子多型、臨床検査. 42:1539-1542.1998. doi:10.11477/mf.1542916900 |
| 13 | 石黒浩毅、有波忠雄．アルコール依存症と遺伝子多型、臨床神経科学. 22:677-679.2004. |
| 14 | 石黒浩毅、有波忠雄．遺伝子解析、臨床精神医学. 33(増刊) 490-494.2005. |
| 15 | 石黒浩毅．アルコール使用障害の遺伝の性差、性差と医療. 3:57-61. 2006. |
| 16 | 石黒浩毅．G蛋白質シグナル調節因子4（RGS4）の遺伝子多型と統合失調症、話題になった遺伝子多型・ハプロタイプのその後（第3回）分子精神医学. 6:435-439.2006. |
| 17 | 堀内泰江、石黒浩毅．PPP3CCとカルシウム関連、Schizophrenia Frontier. 8:29-33.2007. |
| 18 | 石黒浩毅．高増幅効率を特徴とした定量PCRキットによる低発現遺伝子の検出、和光純薬時報. 75:7-8.200z7. |
| 19 | 古賀農人、堀内泰江、森川美幸、石川摩耶、矢崎沙織、岩崎晋也、斎藤利和、樋口進、有波忠雄、石黒浩毅．内因性カナビノイドシステムとアルコール依存症、日本アルコール・薬物医学会雑誌. 43:424-425.2008. |
| 20 | 石黒浩毅、有波忠雄．ゲノミックスと精神神経疾患、老年精神医学雑誌. 20:939-945.2009. |
| 21 | 石黒浩毅、樋口進、斎藤利和、有波忠雄．アルコール依存症と遺伝子、薬物医学会雑誌 44:268-269.2009. |
| 22 | 石黒浩毅、有波忠雄．診断に役立つ遺伝子異常（点突然変異）、精神科臨床評価検査法マニュアル. 39:611-616.2010. |
| 23 | 石黒浩毅．アルコール使用障害の遺伝、カレントテラピー. 28:81.2010. |
| 24 | 菱本明豊、石黒浩毅． 細胞接着因子と精神疾患、日本生物学的精神医学会雑誌. 21:97-104.2010. |
| 25 | 石黒浩毅．ゲノム解析、日本生物学的精神医学会雑誌. 21:27-32. 2010. |
| 26 | 石黒浩毅．アルコール・薬物依存のゲノム研究、日本アルコール関連問題学会雑誌. 14:42-44.2012. |
| 27 | 石黒浩毅．特集：アルコール依存症と関連問題；アルコール依存症と統合失調症、Frontiers in Alcoholism. 4:41-46.2016. |
| 28 | 石黒浩毅．カナビノイドCB2受容体遺伝子、第39回注目の遺伝子 分子精神医学 17:64-66,2017. |
Ｄ．著書
| No. | 著者 ／ 題名 － 発表雑誌 巻：頁（始頁‐終頁），年 |
|---|---|
| 1 | Onaivi ES, Ishiguro H, Lin Z, Akinshola BE, Zhang PW, Uhl GR. Biology of marijuana. From Gene to Behavior. Taylor and Francis. UK. 1-44.2002. |
| 2 | Uhl GR, Ishiguro H, Onaivi E. S, Zhang PW, Akinshola BE, Lin Z, Hope B, Leonard CM, Liu QR. Molecular Neurobiological Methods in Marijuana-Cannabinoid Research. Marijuana and Cannabinoid. Methods Mol Med 123. Research Method and Protocols. Humana Press. USA. 1-17.2006. |
| 3 | Onaivi ES, Ishiguro H, Zhang PW, Lin Z, Akinshola BE, Leonard CM, Chirwa SS, Gong J, Uhl GR. The Brain and Body’s Marijuana and Beyond. Endocannabinoids. Part II: Endocannabinoid Receptor Genetics and Marijuana Use. Taylor & Francis. UK. 57-118.2006. |
| 4 | Onaivi ES, Ishiguro H, Sejal P, Meozzi PA, Myers L, Tagliaferro P, Hope B, Leonard CM, Uhl GR, Brusco A, Gardner E. Methods to study the behavioral effects and expression of CB2 cannabinoid receptor and its gene transcripts in the chronic mild stress model of depression. Methods Mol Med 123. Research Method and Protocols. Humana Press. USA. 291-298.2006. |
| 5 | Ishiguro H, Koga M, Horiucho Y, Onaivi ES, Higuchi S. Development of biomarkers for alcoholism and polysubstance abuse. The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes. Volume IV: Molecular Genetic and Genomic Markers. Springer. USA. 183-193.2009. |
| 6 | Ishiguro H, Leonard CM, Agro S, Onaivi ES. Endocannabinoids: Molecular, Pharmacological, Behavioral and Clinical Features, Chaptor 1: Cannabinoid receptor gene variation in neuropsychiatric disorders. Bentham eBooks. UAE. 3-24.2013. |
| 7 | Onaivi ES, Ishiguro H, Liu QR. Cannabinoids in Neurologic and Mental Disease. Chapter 18: Future perspectives: Cannabinoid CB2 receptor ligands and their therapeutic potential in mental diseases. Elsevier. USA. 425-437.2015. |
| 8 | Onaivi ES, Ishiguro H, Liu QR. Cannabinoid CB2 Receptor Mechanism of Cannabis sativa L. Cannabis sativa L. - Botany and Biotechnology. Springer. USA. 227-247.2017. |
| 9 | Ishiguro H, Horiuchi Y, Koichi Tabata, Qing-Rong Liu, Tadao Arinami, Onaivi ES. Cannabinoid CB2 Receptor Gene and Environmental Interaction in the Development of Psychiatric Disorders. Top 5 Contributions in Molecular Sciences: 2nd Edition, Chapter. Avid Science ebook. India, 2019. |
| 10 | Ishiguro H. An Approach of Transvestism Recognized in Ehlers-Danlos Syndrome: Report of Two Cases. Book Publisher International. 2020 |
| 11 | 石黒浩毅. 依存症と脳－原因か、結果か? VI章-5 精神疾患はどこまで解明されているのか？ 脳バンク 精神疾患の謎を解くために（加藤忠史＆ブレインバンク委員会）光文社新書. 東京. 217-226.2011. |
| 12 | 石黒浩毅. 3章 妊娠期の異常 7節 合併症を有する妊娠 4 精神疾患 母性看護の実践 小林康江、中込さと子、荒木奈緒編 メディカ出版115-116.2021 |
Ｅ．学会発表
| No. | 発表者名、演題、発表学会、発表年月、開催地、発表の種類 （国際は一般発表も含む。国内は特別企画のみ） |
|---|---|
| （国際）※日本国内での開催も含みます。 | |
| ＜特別講演（受賞講演）＞ | |
| 1 | Ishiguro H. NrCAM and addiction., International Brain And Neural Genetics Society meeting. 2010.5 Nova Scotia, CANADA 口頭 |
| ＜シンポジウム＞ | |
| 2 | Ishiguro H, Arinami T. Multicenter studies of genome-wide scan for linkage to schizophrenia in Japan. (Symposium: Schizophrenia), 8th World Congress of Biological Psychiatry. 2005.6 Vienna, Austria 口頭 |
| 3 | Ishiguro H. Genetic profiling for schizophrenia. (Symposium 6: Neurobehavoiral genetics of marijuana use and schizophrenia.). IBANGS. 2007.5 Doorwerth, Holland 口頭 |
| 4 | Ishiguro H, Higuchi S, Arinami T. Genetics of comorbidity in alcoholism and depression (endocannabinoid system), (Synposium: Alcoholism and Depression: Possible common pathology.). 1st APSAAR. 2009.11 Seoul, Korea 口頭 |
| 5 | Ishiguro H. NrCAM and addiction. (Synposium: Genetics of Alcoholism.). 1st APSAAR. 2009.11 Seoul, Korea 口頭 |
| 6 | Ishiguro H. Endocannabinoid system in addiction. (Symposium 8: Addiction neuroscience: human studies & Emerging New Treatments). CINP2013, Special Congress on Addiction. 2013.9 Kuala Lumpur, Malaysia 口頭 |
| 7 | Ishiguro H, Tabata K, Mochizuki C, Onaivi ES. Environmental stressors induce psychosis based on genetic variation of Cannabinoid CB2 Receptors. (Symposium-44: Cannabinoid Receptor (CBR) gene variations in neuropsychiatric disorders). 13th World Congress of Biological Psychiatry. 2017.6 Copenhagen, Denmark 口頭 |
| 8 | Ishiguro H, Tabata K, Mochizuki C, Onaivi ES. Environmental stressors induce psychosis based on genetic variation of Cannabinoid CB2 Receptors. (Symposium: Neurobiology of cannabinoid type 2 receptors). IBNS 28th Annual Meeting.2018.6 Boca Raton, USA 口頭 |
| 9 | Ishiguro H, Tabata K, Mochizuki C, Onaivi ES. Environmental stressors induce psychosis based on genetic variation of Cannabinoid CB2 Receptors. (Symposium: Neurobiology of the endocannabinoid system in psychiatric disorders.). 18th WPA World Congress of Psychiatry, 2018.9. New Mexico, Mexico 口頭 |
| 10 | Ishiguro H. CB2R gene and environmental interaction in the development of psychiatric disorders. 21st WPA World Congress of Psychiatry 2021.10 Virtual 口頭 |
| ＜一般演題＞ | |
| 11 | Ishiguro H, Onaivi ES, Lin Z, Xu F, Otsuki T, Arinami T, Uhl GR. Polymorphic structure of Cannabinoid receptor type1 gene. 30th Annual Meeting of Neuroscience. 2000.10 New Orleans, LA. ポスター |
| 12 | Ishiguro H, Liu QR, Uhl GR. Chromosome 7 association findings in polysubstance abusers: possible association near D7S2420. 31st Annual Meeting of Neuroscience. 2001.11 San Diego, USA. ポスター |
| 13 | Ishiguro H, Gong JP, Drgon T, Liu QR, Walther D, Uhl GR. Human substance abuse vulnerability loci 1: Fine mapping of rSA regions 1-7 reveal haplotypes and candidate genes. 32nd Annual Meeting of Neuroscience. 2002.10 Orlando, USA. ポスター |
| 14 | Ishiguro H, Uhl GR. Allelic variation at genes encoding NrCAM and ligands: associations with substance abuse vulnerability. 52nd Annual Meeting of American Society of Human Genetics. 2002.10 Baltimore, USA. ポスター |
| 15 | Ishiguro H, Uhl GR. Fine - mapping the chromosome 3 reproducible substance abuse vulnerability locus rSA1 implicates the SLC4A7 gene region. 33rd Annual Meeting of Neuroscience. 2003.11 New Orleans, USA. ポスター |
| 16 | Onaivi ES, Colas D, Perchuk A, Zhang PW, Ishiguro H, Taylor RE, Uhl GR, Akinshola BE. Interaction between cannabinoids and abused substances. 33rd Annual Meeting of Neuroscience. 2003.11 New Orleans, USA. ポスター |
| 17 | Mineta M, Ishiguro H, Egan M, Taubman J, Kolachana B, Rowe T, Lipsky R, Uhl GR, Weinberger DR, Goldman D. SGCE, a gene for Myoclonus-dystonia: a possible risk gene for schizophrenia. 33rd Annual Meeting of Neuroscience. 2003.11 New Orleans, USA. ポスター |
| 18 | Zhang PW, Ishiguro H, Onaivi ES, Lin Z, Uhl GR. Human cannabinoid receptor 1 (CB1) gene structure, polymorphisms, and associations with substance abuse. 33rd Annual Meeting of Neuroscience. 2003.11 New Orleans, USA. ポスター |
| 19 | Uhl GR, Walther D, Liu Q, Drgon T, Zhu X, Drgonova J, Polesskaya O, Zhang P, Lin Z, Ishiguro H, Gong J. Convergent human substance abuse vulnerability loci: identification and fine mapping. 33rd Annual Meeting of Neuroscience. 2003.11 New Orleans, USA. ポスター |
| 20 | Ishiguro H, Liu QR, Uhl GR. Fine mapping of a chromosome 7 substance abuse vulnerability locus implicates NrCAM gene regulatory regions. 54th Annual Meeting of American Society of Human Genetics. 2003.10 Los Angeles, USA. ポスター |
| 21 | Mineta M, Ishiguro H, Egan M, Taubman J, Kolachana B, Rowe T, Lipsky R, Uhl GR, Weinberger DR, Goldman D. -sarcoglycan, a gene in which variants cause myoclonus-dystonia syndrome, may also contain schizophrenia vulnerability variants. 54th Annual Meeting of American Society of Human Genetics. 2003.11 Los Angeles, USA 口頭 |
| 22 | Horiuchi Y, Nakayama J, Ishiguro H, Ohtsuki T, Toyota T, Yamada K, Nankai M, Shibuya H, Yoshikawa T, Arinami T. Possible association between haplotype of the GABA-A receptor alpha 1 subunit gene (GABARA1) and mood disorders. 54th Annual Meeting of American Society of Human Genetics. 2003.11 Los Angeles, USA 口頭 |
| 23 | Ishiguro H, Liu Q, Gong J, Sakurai T, Grumet M, Uhl GR. NrCAM in substance abuse: Genetic and molecular biologic evidence in human and animal models. 34th Annual Meeting of Neuroscience. 2004.10 San Diego, USA. ポスター |
| 24 | Ishiguro H, Arinami T. Multicenter studies of genome-wide scan for linkage to schizophrenia in Japan. World Congress of Biological Psychiatry. 2005.6 Vienna, Austria ポスター |
| 25 | Ishiguro H, Liu QR, Gong JP, Hall FS, Ujike H, Morales M, Sakurai T, Grumet M, Uhl GR. NrCAM in opiate vulnerability: positional cloning, opiate-regulation, haplotype-specific expression and altered morphine reward in knockout mice. The international Narcotics Research conference 2005. Annapolis, USA ポスター |
| 26 | Ishiguro H, Hall S, Sakurai T, Grumet M, Uhl G.R. Morphine-NrCAM interactions relevant to addiction and pain. 35th Annual Meeting of Neuroscience. 2005.11 Washington DC, USA. ポスター |
| 27 | Ishiguro H, Iwasaki S, Teasenfitz L, Higuchi S, Arinami T, Onaivi ES. Association of cannabinoid receptor CB2 gene with alcoholism and development of alcohol preference. International Behavioral Neuroscience Society. 2006.10 Whistler, Canada ポスター |
| 28 | Ishiguro H, Iwasaki S, Teasenfitz L, Higuchi S, Arinami T, Onaivi ES. Involvement of cannabinoid CB2 receptor in alcohol preference in mice and alcoholism in humans. World Congresses of Psychiatric Genetics. 2006.10 Cagliari, Italy ポスター |
| 29 | Ishiguro H, Horiuchi Y, Hall S, Sakurai T, Grumet M, Higuchi S, Uhl GR, Arinami T. Nrcam knockout mice alter their novelty-seeking behavior. 36th Annual Meeting of Neuroscience. 2006.10 Atlanta, USA ポスター |
| 30 | Ishiguro H, Horiuchi Y, Hall S, Sakurai T, Uhl GR, Arinami T. Molecular pathway related to Nrcam underlying addiction vulnerability. 37th Annual Meeting of Neuroscience. 2007.11 San Diego, USA. ポスター |
| 31 | Ishiguro H, Koga M, Horiuchi Y, Noguchi E, Arai M, Niizato K, Iritani S, Itokawa M, Inada T, Iwata N, Ozaki N, Ujike H, Kunugi H, Sasaki T, Takahashi M, Watanabe Y, Someya T, Kakita A, Takahashi H, Nawa H, Arinami T. Supportive evidence for reduced expression of GNB1L in schizophrenia. World Congress of Psychiatric Genetics. 2008.10 Osaka. ポスター |
| 32 | Ishiguro H, Horiuchi Y, Shu A, Ishikawa M, Koga M, Imai K, Onaivi ES, Takahashi M, Kakita A, Takahashi H, Nawa H, Arinami T. Brain cannabinoid CB2 receptor and schizophrenia. 38th Annual Meeting of Neuroscience. 2008.11 Washington DC, USA. ポスター |
| 33 | Ishiguro H, Onaivi ES, Koga M, Horiuchi Y, Komaki G, Ishikawa T, Suzuki M, Watanabe Y, Ando T, Higuchi S, Arinami T. GPR55 and anorexia nervosa. 39th Annual Meeting of Neuroscience. 2009.10 Chicago, USA. ポスター |
| 34 | Ishiguro H, Leonard CM, Barda O, Uhl GR, Onaivi ES. Cannabinoid receptor gene variation in neuropsychiatric disorders. 41st Annual Meeting of Neuroscience. 2011.11 Washington DC, USA. ポスター |
| 35 | Ishiguro H, Uhl GR, Onaivi ES. Cannabinoid receptors: Gene structures, SNPs, CNVs, CPG islands, microRNA regulation and variation in neuropsychiatric disorders. 42nd Annual Meeting of Neuroscience. 2012.11 New Orleans, USA. ポスター |
| 36 | Ishiguro H, Tabata K, Buckley N, Uemura T, Motohashi N, Liu QR, Onaivi ES. Behavioral roles of cannabinoid type 2 receptor in depression. 43rd Annual Meeting of Neuroscience. 2013.11 San Diego, USA. ポスター |
| 37 | Ishiguro H, Tabata K, Sakurai T, Grumet M, Onaivi ES, Uhl GR, Motohashi N. NrCAM regulating neural systems in addiction vulnerability 44th Annual Meeting of Neuroscience. 2014.11 Washington DC, USA ポスター |
| 38 | Ishiguro H, Tabata K, Buckley N, Okabe A, Motohashi N, Onaivi ES. Environmental stressors induce schizophrenia-like symptoms based on genetic dysfunction of cannabinoid type 2 receptor and K-Cl cotransporter KCC2. 45th Annual Meeting of Neuroscience. 2015.10 Chicago, USA ポスター |
| 39 | Ishiguro H, Sakurai T, Motohashi N, Onaivi E. NrCAM regulating neural systems in addiction vulnerability. 46th Annual Meeting of Neuroscience. 2016.11 San Diego, USA ポスター |
| 40 | Onaivi ES, Zhang H, Gardner EL, Ishiguro H, Xi ZX, Liu QR. Cannabinoid type 2 receptors in brain dopamine neurons modulates anxiety-like and psychostimulant behaviors in floxed DAT-Cnr2 mouse model. 46th Annual Meeting of Neuroscience. 2016.11 San Diego, USA ポスター |
| 41 | Ishiguro H, Onaivi ES, Canseco-Alba A, Zang H, Gardener EL, Xi ZX, Liu QR. Cannabinoid type 2 receptors in brain dopamine neurons modulates anxiety-like and psychostimulant behaviors in floxed DAT-Cnr2 mouse model. (Symposium: Neurobiology of cannabinoid type 2 receptors). IBNS 27th Annual Meeting. 2017.6 Hiroshima ポスター |
| 42 | Ishiguro H, Tabata K, Mochizuki C, Onaivi ES. Environmental stresses and psychiatric disorders based on genetic dysfunction of cannabinoid CB2 receptor. 47th Annual Meeting of Neuroscience. 2017.11 Washington DC, USA ポスター |
| 43 | Ishiguro H, Honobe N, Suzuki T, Tamai M, Nakane T. Transvestism recognized in Ehlers-Danlos syndrome: Report of two cases. Scientific Meeting on the Rarer Types of EDS. 2019.11 Tokyo 口頭 |
| 44 | Ishiguro H. Tabata K, Horiuchi Y, Liu QR, Onaivi ES. Alcohol preference and depression in CNR2 knockout mice. (Session XII: Marijuana and Cannabinoids), IDAR 7th Annual Meeting. 2019.9 Casablanca, Morocco. 口頭 |
| （国内） | |
| ＜シンポジウム＞ | |
| 1 | 石黒浩毅．アルコール依存症におけるカナビノイド神経の役割. (シンポジウム:アルコール依存)．第18回日本アルコール精神医学会・第9回ニコチン・薬物依存研究フォーラム 平成18年度合同学術集会2006.9 横浜 口頭 |
| 2 | 石黒浩毅．依存症に関わる分子の解明.（シンポジウム:アルコール依存）．第14回日本精神・行動遺伝医学会. 2006.11 つくば 口頭 |
| 3 | 菱本明豊、石黒浩毅．細胞接着因子と精神疾患（シンポジウム：死後脳研究－その成果と課題）．第31回日本生物学的精神医学会. 2009.4 神戸 口頭 |
| 4 | 石黒浩毅, 樋口進, 齊藤利和, 有波忠雄．アルコール依存症と遺伝子 （シンポジウム2：アルコール・薬物関連障害の生物学的研究の動向）．第20回日本アルコール精神医学会. 2009.9 横浜 口頭 |
| 5 | 石黒浩毅．アルコール・薬物依存のゲノム研究. 分科会④「生物学的研究から新たな治療戦略へ」．第33回日本アルコール関連問題学会2011.7 佐賀 口頭 |
| 6 | 石黒浩毅、Onaivi ES, 三宅邦夫、中山桜、田畑光一、曽我部博文、櫻井武、久保田健夫、本橋伸高．神経接着因子NrCAMが形成する依存脳の神経ネットワークと依存表現型の解明．（シンポジウム11：アルコール・薬物依存症の神経生物学・遺伝学的研究の動向―若手精神科医を中心に―）．平成27年度 アルコール・薬物依存関連学会合同学術総会 第50回日本アルコール・薬物医学会 第37回日本アルコール関連問題学会 第27回日本依存神経精神科学会2015.10 神戸 口頭 |
| 7 | 石黒浩毅、大橋由明．COVID-19災禍による産後うつ精神科医療への影響 第18回日本うつ病学会／第21回日本認知療法・認知行動療法学会 2021.7 横浜 口頭 |
| 8 | 石黒浩毅、AYA世代に対する遺伝外来：着床前遺伝学的検査をめぐるクライアントの葛藤と精神科医療のあり方について 第119回日本精神神経学会学術総会/医療倫理委員会シンポジウム 2023.6 横浜 口頭 |
| ＜ワークショップ＞ | |
| 1 | Ishiguro H, Arinami T, Saito T, Shibuya H. Association study between the VNTR polymorphism in the third exon of dopamine D4 receptor gene and clinical features in alcoholics. Cross Cultural Collaborations in Alcohol-Use Disorders: New Avenues for Research – United States/Japan Joint Workshop. 1998 Tokyo ポスター |
| 2 | Ishiguro H, Arinami T, Saito T, Shibuya H. Association study between any genetic polymorphisms in the dopaminergic system and the serotoninergic system, and alcoholism. Cross Cultural Collaborations in Alcohol-Use Disorders: New Avenues for Research – United States/Japan Joint Workshop. 1998 Tokyo ポスター |
| 3 | Ishiguro H, Arinami T. NrCAM and addiction-related behaviors. Naito conference. 2011.10 Yamanashi ポスター |
| ＜その他；CREST成果報告会＞ | |
| 4 | Ishiguro H, Horiuchi Y, Koga M, Imai K, Ishikawa M, Morikawa M, Suzuki Y, Shu A, Noguchi E, Arai M, Niizato K, Iritani S, Itokawa M, Inada T, Iwata N, Ozaki N, Ujike H, Kunugi H, Sasaki T, Takahashi M, Watanabe Y, Someya T, Kakita A, Takahashi H, Nawa H, Arinami T: GWASを支える統合失調症の解析：薬理学的知見および染色体異常症候群の類縁症状の知見から、CREST成果発表2008.7 東京 口頭 |
Ｆ．その他
| No. | 受賞、発明、特許、地域社会への貢献業績、その他 |
|---|---|
| No. | 受賞、発明、特許、地域社会への貢献業績、その他 |
| 受賞 | |
| 1 | Lilly Molecular Psychiatry Award, 2004.8.3 |
| 2 | 日本臨床精神薬理学会学会奨励賞Dr. Paul Janssen Research Award, 2008.10.3 |
| 3 | IBANGS Young Investigator Award, 2010.5.16 |
| 4 | 第32回内藤コンファレンス「こころの機能と疾患の分子機構｣ポスター賞, 2011.10.21 |
| 発明、特許 | |
| 1 | 産後うつの判定方法 特許出現公開番号P2022-101776 |
| 地域社会への貢献業績 | |
| ＜パンフレット＞ | |
| 1 | 北村千章、早川統子、榎本淳子、石黒浩毅、中込さと子、林伸彦、安河内聡、稲葉雄二、桐生徹．22ｑ11.2就学サポート、2019. |
| 2 | 立花良之（執筆協力）、石黒浩毅（監修）. 妊産婦メンタルヘルス対応マニュアル、2020. |
| ＜広報誌＞ | |
| 1 | 石黒浩毅．「これってうつかな？」、みなさんの健康欄 山梨県中央市配布冊子「ちゅうおう2012 No.78」および「広報 昭和8月号」2012.8. |
| 2 | 石黒浩毅．遺伝子とアルコール問題の関係、アル健協NEWS&REPORTS 社団法人アルコール健康医学協会17:7-10, 2012. |